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Joined 3 years ago
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Cake day: June 24th, 2023

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  • The primary cause of lead’s toxicity is its interference with a variety of enzymes because it binds to sulfhydryl groups found on many enzymes.[22] Part of lead’s toxicity results from its ability to mimic other metals that take part in biological processes … Among the essential metals that lead displaces in this way are calcium, iron, and zinc.[186]

    The brain is the organ most sensitive to lead exposure.[77] Lead can pass through the endothelial cells at the blood brain barrier because it can substitute for calcium ions and be taken up by calcium-ATPase pumps.[203]

    The targeting of NMDA receptors is thought to be one of the main causes for lead’s toxicity to neurons.[202]

    The half-life of lead in bone has been estimated as years to decades, and bone can introduce lead into the bloodstream long after the initial exposure is gone.[182][183][184] The half-life of lead in the blood in men is about 40 days, but it may be longer in children and pregnant women, whose bones are undergoing remodeling, which allows the lead to be continuously re-introduced into the bloodstream.[26]

    https://en.wikipedia.org/wiki/Lead_poisoning

    Stainless steel is generally considered to be biologically inert. However, during cooking, small amounts of nickel and chromium leach out of new stainless steel cookware into highly acidic food.[115] Nickel can contribute to cancer risks—particularly lung cancer and nasal cancer.[116][117] However, no connection between stainless steel cookware and cancer has been established.

    https://en.wikipedia.org/wiki/Stainless_steel

    Lead is very different in its toxicity. Chromium is not nearly as toxic, and in fact trivalent chromium is an essebtial nutrient:

    Trivalent chromium is a trace mineral that is essential to human nutrition

    https://en.wikipedia.org/wiki/Chromium_toxicity

    Of course wikipedia isn’t an official source, but almost all statement’s link to reliable sources





  • Bazoogle@lemmy.worldtoSelfhosted@lemmy.worldBentoPDF v1.16.0
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    30 days ago

    I’m running it and it screams vibe coded. The maintainer worked for an AI company before this as well, so it wouldn’t surprise me if it is mostly AI written. It’s buggy and clunky, despitr having a clean UI. The features are random and incomplete. The PDF Form creator is a joke. The signature portion doesn’t work. The “simple” mode really should be default. The website has big company bames in it saying “used by peoplr working at” which is just a bullshit and unimportant thing to say to put big companies logos on the site. Also those same logos aren’t currently removed from the simple mode probably because the AI didn’t consider that when it added the feature.

    I know it’s a new project, so I am hoping it gets better. I have wanted a tool exactly like this for so long. Unfortunate that it’s a result of AI, but beggars can’t be choosers



  • I agree it’s a valid complaint, as in it’s expected to be complained about. It’s not so valid to expect the pharmacy to actually change anything. There are a million and one solutions to their problem. If it’s just the sharp edges, they can clip those off with some rounded nail clippers. If they have trouble getting them out of the pack, there are any number of tools/solutions to get the pill out to make it easier.

    I think this post is valid as mildly infuriating, since it’s not that big of a deal. But calling it an infuriating puzzle is pretty wild. Idk what puzzles you are doing